About Z-Pix™ — Nicotine Toothpicks Made in the USA

About Z-Pix™

Z-Pix™ (formerly Zippix®) has been making nicotine toothpicks since 1993, the longest track record of any brand in the category. We pressure-infuse wood toothpicks with plant-derived nicotine and natural flavors, then ship them from the United States.

What we make

  • Nicotine toothpicks in six core flavors: Cinnamon, Mocha, Peppermint Watermelon, Sweet Whisky, Spice Island Clove, and Sweet Wood. Available in 20-count grab pouches and 100-count carry tubes.
  • BIG Z-Pix™ — stronger toothpicks for bigger cravings, same flavors.
  • Energy Toothpicks — nicotine-free caffeine + B12 toothpicks for a smokeless energy boost.
  • Rejuvinex™ — flavor sprays that refresh any toothpick.

How it works

Place a Z-Pix™ nicotine toothpick between your cheek and gums. Lightly chew or suck on it. Nicotine absorbs through the oral mucosa within seconds, lasting 20–30 minutes per pick. No smoke, no vapor, no ash.

Making these since 1993

Z-Pix™ was founded by Marcus Kruk. Nicotine toothpicks were first produced in 1993 through a compounding pharmacy he owned, where they were provided to patients on the recommendation of pulmonary physicians and respiratory therapists. Two companies under his ownership have sold them continuously since.

Nicotine toothpicks were a category of one for most of their history, and Z-Pix™ built it. We have been pressure-infusing toothpicks since 1993, long before oral nicotine became a category other brands wanted into.

That run is why the flavors hold up across a full session rather than fading in two minutes, and why the range runs to six core flavors, a stronger BIG line, and pack sizes from 20 up to 600 picks. It is a manufacturing process with thirty years of refinement behind it.

Today Z-Pix™ carries a 4.8 out of 5 rating across more than 2,300 customer reviews, the deepest public review base in the category.

What is in them

Every Z-Pix™ product page lists its full ingredients. The base is vegetable-based glycerine, sucralose, sodium citrate, potassium sorbate and plant-derived nicotine at 2mg or 3mg per toothpick depending on flavor, plus the flavor itself.

All Z-Pix™ toothpicks are gluten free, non-GMO, and every ingredient is Kosher certified. They are third-party lab tested and FDA registered.

Why we exist

Z-Pix™ began because the people who use nicotine deserve a discreet option that works in places where smoking, vaping, and even pouches don't. Bars, restaurants, sporting events, the office, around family — Z-Pix™ goes everywhere you do.

How we make Z-Pix™

Each Z-Pix™ toothpick is pressure-infused, which is how we get the flavor to last and the nicotine to be evenly distributed across the wood. Every flavor is quality-tested by independent third-party labs. We are FDA-registered. Production happens in the USA.

Where to find us

Order direct at zippixtoothpicks.com. Domestic shipping is free on qualifying orders and ships within 1–2 business days. Subscriptions save 10%, and you can change flavor, skip, or cancel anytime.

21+ only

Z-Pix™ products are for adults 21 and over. Nicotine is a highly addictive chemical. Not for use during pregnancy or by people with heart conditions or other contraindications. Consult your doctor before use.